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Rapid c-myc mRNA degradation does not require (A + U)-rich sequences or complete translation of the mRNA.
The c-myc proto-oncogene encodes a highly unstable mRNA. Stabilized, truncated myc transcripts have been found in several human and murine tumors of hematopoietic origin. Recently, two tumors expressing 3' truncated c-myc mRNAs that were five times more stable than normal myc transcripts, were...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
1991
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC329447/ https://ncbi.nlm.nih.gov/pubmed/1645870 |
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