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Rapid c-myc mRNA degradation does not require (A + U)-rich sequences or complete translation of the mRNA.

The c-myc proto-oncogene encodes a highly unstable mRNA. Stabilized, truncated myc transcripts have been found in several human and murine tumors of hematopoietic origin. Recently, two tumors expressing 3' truncated c-myc mRNAs that were five times more stable than normal myc transcripts, were...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Laird-Offringa, I A, Elfferich, P, van der Eb, A J
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1991
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329447/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1645870/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.9.2387
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