Rapid c-myc mRNA degradation does not require (A + U)-rich sequences or complete translation of the mRNA.
The c-myc proto-oncogene encodes a highly unstable mRNA. Stabilized, truncated myc transcripts have been found in several human and murine tumors of hematopoietic origin. Recently, two tumors expressing 3' truncated c-myc mRNAs that were five times more stable than normal myc transcripts, were descr...
Gardado en:
| Publicado en: | Nucleic Acids Res |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
1991
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| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329447/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1645870/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.9.2387 |
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