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An Automated Method to Quantify Microglia Morphology and Application to Monitor Activation State Longitudinally In Vivo
Microglia are specialized immune cells of the brain. Upon insult, microglia initiate a cascade of cellular responses including a characteristic change in cell morphology. To study the dynamics of microglia immune response in situ, we developed an automated image analysis method that enables the quan...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3294422/ https://ncbi.nlm.nih.gov/pubmed/22457705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031814 |
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