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Constitutive type I interferon modulates homeostatic balance through tonic signaling

Interferons (IFNs) were discovered nearly 60 years ago as a family of cytokines induced during and protecting from viral infection. They have been documented to play essential roles in numerous physiological processes beyond innate antiviral defense, including immunomodulation, regulation of the cel...

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Detalhes bibliográficos
Main Authors: Gough, Daniel J., Messina, Nicole L., Clarke, Christopher J.P., Johnstone, Ricky W., Levy, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294371/
https://ncbi.nlm.nih.gov/pubmed/22365663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.01.011
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