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Constitutive IFNα/β signaling maintains expression of signaling intermediaries for efficient cytokine responses

Interferons (IFNs) are a family of immunoregulatory cytokines with important roles in anti-viral and anti-tumor responses. Type I and II IFNs bind distinct receptors and are associated with different stages of the immune response. There is however, considerable crosstalk between these two cytokines...

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Detalhes bibliográficos
Publicado no:JAKSTAT
Main Authors: Messina, Nicole L., Clarke, Christopher J. P., Johnstone, Ricky W.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964971/
https://ncbi.nlm.nih.gov/pubmed/27512617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21623996.2016.1173804
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