Aberrant Tubuloglomerular Feedback and HIF-1α Confer Resistance to Ischemia after Subtotal Nephrectomy

Nephron loss in a diseased kidney invokes adaptations in the remaining nephrons. Whether and how these adaptations condition the response of the kidney to injury is not known. We examined the susceptibility of the kidney after subtotal (5/6th) nephrectomy (STN) to ischemic injury in rats. GFR in STN...

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Bibliographic Details
Main Authors: Singh, Prabhleen, Blantz, Roland C., Rosenberger, Christian, Gabbai, Francis B., Schoeb, Trenton R., Thomson, Scott C.
Format: Artigo
Language:Inglês
Published: American Society of Nephrology 2012
Subjects:
Basic Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294306/
https://ncbi.nlm.nih.gov/pubmed/22266667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011020130
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