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Aberrant Tubuloglomerular Feedback and HIF-1α Confer Resistance to Ischemia after Subtotal Nephrectomy

Nephron loss in a diseased kidney invokes adaptations in the remaining nephrons. Whether and how these adaptations condition the response of the kidney to injury is not known. We examined the susceptibility of the kidney after subtotal (5/6th) nephrectomy (STN) to ischemic injury in rats. GFR in STN...

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Main Authors: Singh, Prabhleen, Blantz, Roland C., Rosenberger, Christian, Gabbai, Francis B., Schoeb, Trenton R., Thomson, Scott C.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Nephrology 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294306/
https://ncbi.nlm.nih.gov/pubmed/22266667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011020130
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