IQGAP1 regulates ERK1/2 and AKT signalling in the heart and sustains functional remodelling upon pressure overload

AIMS: The Raf-MEK1/2-ERK1/2 (ERK1/2—extracellular signal-regulated kinases 1/2) signalling cascade is crucial in triggering cardiac responses to different stress stimuli. Scaffold proteins are key elements in coordinating signalling molecules for their appropriate spatiotemporal activation. Here, we...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sbroggiò, Mauro, Carnevale, Daniela, Bertero, Alessandro, Cifelli, Giuseppe, De Blasio, Emanuele, Mascio, Giada, Hirsch, Emilio, Bahou, Wadie F., Turco, Emilia, Silengo, Lorenzo, Brancaccio, Mara, Lembo, Giuseppe, Tarone, Guido
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2011
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294280/
https://ncbi.nlm.nih.gov/pubmed/21493702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvr103
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