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The “Death” Adaptor CRADD/RAIDD Targets BCL10 and Suppresses Agonist-Induced Cytokine Expression in T Lymphocytes
The expression of proinflammatory cytokines and chemokines in response to T cell receptor (TCR) agonists is regulated by the CARMA1 signalosome through the coordinated assembly of complexes containing the BCL10 adaptor protein. We describe a novel mechanism to negatively regulate the CARMA1 signalos...
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| Asıl Yazarlar: | , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2012
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3294148/ https://ncbi.nlm.nih.gov/pubmed/22323537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101502 |
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