The “Death” Adaptor CRADD/RAIDD Targets BCL10 and Suppresses Agonist-Induced Cytokine Expression in T Lymphocytes

The expression of proinflammatory cytokines and chemokines in response to T cell receptor (TCR) agonists is regulated by the CARMA1 signalosome through the coordinated assembly of complexes containing the BCL10 adaptor protein. We describe a novel mechanism to negatively regulate the CARMA1 signalos...

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Bibliographic Details
Main Authors: Lin, Qing, Liu, Yan, Moore, Daniel J., Elizer, Sydney K., Veach, Ruth A., Hawiger, Jacek, Ruley, H. Earl
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294148/
https://ncbi.nlm.nih.gov/pubmed/22323537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101502
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