Alternaria induces STAT-6 dependent acute airway eosinophila and epithelial FIZZ1 expression that promotes airway fibrosis and epithelial thickness

The fungal allergen, Alternaria, is specifically associated with severe asthma, including life-threatening exacerbations. To better understand the acute innate airway response to Alternaria, naïve WT mice were challenged once intranasally with Alternaria. Naïve WT mice developed significant BAL eosi...

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Main Authors: Doherty, Taylor A., Khorram, Naseem, Sugimoto, Kotaro, Sheppard, Dean, Rosenthal, Peter, Youn Cho, Jae, Pham, Alexa, Miller, Marina, Croft, Michael, Broide, David H.
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294141/
https://ncbi.nlm.nih.gov/pubmed/22327070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101632
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