CD27 deficiency is associated with combined immunodeficiency and persistent symptomatic EBV viremia

BACKGROUND: CD27 is a lymphocyte co-stimulatory molecule that regulates T, NK B, and plasma cell function, survival and differentiation. Based on its function and expression pattern we considered CD27 as a candidate gene in patients with hypogammaglobulinemia. OBJECTIVE: Description of the clinical...

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Hauptverfasser: van Montfrans, Joris M., Hoepelman, Andy I. M., Otto, Sigrid, van Gijn, Marielle, van de Corput, Lisette, de Weger, Roel A., Monaco-Shawver, Linda, Banerjee, Pinaki P., Sanders, Elisabeth A.M., Jol-van der Zijde, Cornelia M., Betts, Michael R., Orange, Jordan S., Bloem, Andries C., Tesselaar, Kiki
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294016/
https://ncbi.nlm.nih.gov/pubmed/22197273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2011.11.013
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