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Effect of Size and Heterogeneity of Samples on Biomarker Discovery: Synthetic and Real Data Assessment

MOTIVATION: The identification of robust lists of molecular biomarkers related to a disease is a fundamental step for early diagnosis and treatment. However, methodologies for the discovery of biomarkers using microarray data often provide results with limited overlap. These differences are imputabl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Di Camillo, Barbara, Sanavia, Tiziana, Martini, Matteo, Jurman, Giuseppe, Sambo, Francesco, Barla, Annalisa, Squillario, Margherita, Furlanello, Cesare, Toffolo, Gianna, Cobelli, Claudio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293892/
https://ncbi.nlm.nih.gov/pubmed/22403633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032200
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