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Modification of EGF-Like Module 1 of Thrombospondin-1, an Animal Extracellular Protein, by O-Linked N-Acetylglucosamine

Thrombospondin-1 (TSP-1) is known to be subject to three unusual carbohydrate modifications: C-mannosylation, O-fucosylation, and O-glucosylation. We now describe a fourth: O-β-N-acetylglucosaminylation. Previously, O-β-N-acetylglucosamine (O-β-GlcNAc) was found on a threonine in the loop between th...

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Detalhes bibliográficos
Main Authors: Hoffmann, Brian R., Liu, Yuanyuan, Mosher, Deane F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293841/
https://ncbi.nlm.nih.gov/pubmed/22403705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032762
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