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Influences of the N700S Thrombospondin-1 Polymorphism on Protein Structure and Stability

Thrombospondins (THBSs) are multimodular, secreted proteins characterized by a signature domain comprising a unique set of 13 calcium-binding repeats flanked by epidermal growth factor (EGF)-like and lectin-like modules. A polymorphism that changes a conserved Asn to Ser at residue 700 in the most N...

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Detalhes bibliográficos
Main Authors: Carlson, C. Britt, Liu, Yuanyuan, Keck, James L., Mosher, Deane F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2459288/
https://ncbi.nlm.nih.gov/pubmed/18499674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800223200
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