Long-term Restoration of Cardiac Dystrophin Expression in Golden Retriever Muscular Dystrophy Following rAAV6-mediated Exon Skipping

Although restoration of dystrophin expression via exon skipping in both cardiac and skeletal muscle has been successfully demonstrated in the mdx mouse, restoration of cardiac dystrophin expression in large animal models of Duchenne muscular dystrophy (DMD) has proven to be a challenge. In large ani...

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Bibliografski detalji
Glavni autori: Bish, Lawrence T, Sleeper, Meg M, Forbes, Sean C, Wang, Bingjing, Reynolds, Caryn, Singletary, Gretchen E, Trafny, Dennis, Morine, Kevin J, Sanmiguel, Julio, Cecchini, Sylvain, Virag, Tamas, Vulin, Adeline, Beley, Cyriaque, Bogan, Janet, Wilson, James M, Vandenborne, Krista, Kornegay, Joe N, Walter, Glenn A, Kotin, Robert M, Garcia, Luis, Sweeney, H Lee
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2012
Teme:
Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293605/
https://ncbi.nlm.nih.gov/pubmed/22146342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.264
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