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Fibronectin Induces Endothelial Cell Migration through β1 Integrin and Src-dependent Phosphorylation of Fibroblast Growth Factor Receptor-1 at Tyrosines 653/654 and 766

The extracellular matrix microenvironment regulates cell phenotype and function. One mechanism by which this is achieved is the transactivation of receptor tyrosine kinases by specific matrix molecules. Here, we demonstrate that the provisional matrix protein, fibronectin (FN), activates fibroblast...

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Detalhes bibliográficos
Main Authors: Zou, Li, Cao, Sheng, Kang, Ningling, Huebert, Robert C., Shah, Vijay H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293564/
https://ncbi.nlm.nih.gov/pubmed/22247553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.304972
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