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Protein Arginine Methyltransferase 5 (PRMT5) Signaling Suppresses Protein Kinase Cδ- and p38δ-dependent Signaling and Keratinocyte Differentiation

PKCδ is a key regulator of keratinocyte differentiation that activates p38δ phosphorylation leading to increased differentiation as measured by an increased expression of the structural protein involucrin. Our previous studies suggest that p38δ exists in association with protein partners. A major go...

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Detalhes bibliográficos
Main Authors: Kanade, Santosh R., Eckert, Richard L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293539/
https://ncbi.nlm.nih.gov/pubmed/22199349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.331660
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