Ascorbate protects against vascular leakage in cecal ligation and puncture-induced septic peritonitis

Vascular leakage in multiple organs is a characteristic pathological change in sepsis. Our recent study revealed that ascorbate protects endothelial barrier function in microvascular endothelial cell monolayers through inhibiting serine/threonine protein phosphatase 2A (PP2A) activation (Han M, Pend...

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Библиографические подробности
Главные авторы: Zhou, Gang, Kamenos, George, Pendem, Suresh, Wilson, John X., Wu, Feng
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2012
Предметы:
Fluid and Electrolyte Homeostasis
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293508/
https://ncbi.nlm.nih.gov/pubmed/22116513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00153.2011
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