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Nordihydroguaiaretic acid reduces secondary organ injury in septic rats after cecal ligation and puncture

BACKGROUND: Nordihydroguaiaretic acid (NDGA) is a plant extract that has been shown to act as a free radical scavenger and pluripotent inhibitor of pro-inflammatory cytokines, two major cellular processes involved in the pathophysiology of sepsis. We investigated whether NDGA would improve markers o...

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Publicat a:PLoS One
Autors principals: Zubrow, Michael E., Margulies, Susan S., Yehya, Nadir
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7425931/
https://ncbi.nlm.nih.gov/pubmed/32790786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0237613
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