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ABCB1 Genotype and CSF β-Amyloid in Alzheimer Disease

The ABCB1 gene, coding for the efflux transporter P-glycoprotein (PGP), is a candidate gene for Alzheimer disease (AD). P-glycoprotein is heavily expressed at the blood–brain barrier, where it mediates the efflux of β-amyloid (Aβ) from the brain. In this study, we investigated a possible association...

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Bibliografski detalji
Glavni autori: Kohen, R., Shofer, J. B., Korvatska, O., Petrie, E. C., Wang, L. Y., Schellenberg, G. D., Peskind, E. R., Wilkinson, C. W.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293495/
https://ncbi.nlm.nih.gov/pubmed/21478475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0891988711402325
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