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α7 Nicotinic Acetylcholine Receptor Agonism Confers Neuroprotection Through GSK-3β Inhibition in a Mouse Model of Intracerebral Hemorrhage

BACKGROUND AND PURPOSE: Perihematomal edema formation and consequent cell death contribute to the delayed brain injury evoked by intracerebral hemorrhage (ICH). In this study we aimed to evaluate the effect of α7 nicotinic acetylcholine receptor (α7nAChR) stimulation, on behavior, brain edema and ne...

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書誌詳細
主要な著者: Krafft, Paul R., Altay, Orhan, Rolland, William B., Duris, Kamil, Lekic, Tim, Tang, Jiping, Zhang, John H.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293395/
https://ncbi.nlm.nih.gov/pubmed/22207510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.111.639989
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