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PCGF Homologs, CBX Proteins, and RYBP Define Functionally Distinct PRC1 Family Complexes
The heterogeneous nature of mammalian PRC1 complexes has hindered our understanding of their biological functions. Here, we present a comprehensive proteomic and genomic analysis that uncovered six major groups of PRC1 complexes each containing a distinct PCGF subunit, a RING1A/B ubiquitin ligase, a...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3293217/ https://ncbi.nlm.nih.gov/pubmed/22325352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.01.002 |
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