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PCGF Homologs, CBX Proteins, and RYBP Define Functionally Distinct PRC1 Family Complexes

The heterogeneous nature of mammalian PRC1 complexes has hindered our understanding of their biological functions. Here, we present a comprehensive proteomic and genomic analysis that uncovered six major groups of PRC1 complexes each containing a distinct PCGF subunit, a RING1A/B ubiquitin ligase, a...

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Detalhes bibliográficos
Main Authors: Gao, Zhonghua, Zhang, Jin, Bonasio, Roberto, Strino, Francesco, Sawai, Ayana, Parisi, Fabio, Kluger, Yuval, Reinberg, Danny
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293217/
https://ncbi.nlm.nih.gov/pubmed/22325352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.01.002
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