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Macrophage binding to receptor VCAM-1 transmits survival signals in breast cancer cells that invade the lungs

Aberrant expression of vascular cell adhesion molecule-1 (VCAM-1) in breast cancer cells is associated with lung relapse, but the role of VCAM-1 as a mediator of metastasis has remained unknown. We report that VCAM-1 provides a survival advantage to breast cancer cells that infiltrate leukocyte-rich...

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Detalhes bibliográficos
Main Authors: Chen, Qing, Zhang, Xiang H.-F., Massagué, Joan
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293160/
https://ncbi.nlm.nih.gov/pubmed/22014578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2011.08.025
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