Dynamic, adaptive changes in MAO-A binding after alterations in substrate availability: an in vivo [(11)C]-harmine positron emission tomography study

Monoamine oxidase A (MAO-A) is an important target in the pathophysiology and therapeutics of major depressive disorder, aggression, and neurodegenerative conditions. We measured the effect of changes in MAO-A substrate on MAO-A binding in regions implicated in affective and neurodegenerative diseas...

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Detalhes bibliográficos
Main Authors: Sacher, Julia, Rabiner, Eugenii A, Clark, Michael, Rusjan, Pablo, Soliman, Alexandra, Boskovic, Rada, Kish, Stephen J, Wilson, Alan A, Houle, Sylvain, Meyer, Jeffrey H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293124/
https://ncbi.nlm.nih.gov/pubmed/22186668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2011.184
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