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Kollidon VA64, a membrane-resealing agent, reduces histopathology and improves functional outcome after controlled cortical impact in mice

Loss of plasma membrane integrity is a feature of acute cellular injury/death in vitro and in vivo. Plasmalemma-resealing agents are protective in acute central nervous system injury models, but their ability to reseal cell membranes in vivo has not been reported. Using a mouse controlled cortical i...

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Detalhes bibliográficos
Main Authors: Mbye, Lamin H, Keles, Eyup, Tao, Luyang, Zhang, Jimmy, Chung, Joonyong, Larvie, Mykol, Koppula, Rajani, Lo, Eng H, Whalen, Michael J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293116/
https://ncbi.nlm.nih.gov/pubmed/22086196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2011.158
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