Early and progressive impairment of spinal blood flow–glucose metabolism coupling in motor neuron degeneration of ALS model mice

The exact mechanism of selective motor neuron death in amyotrophic lateral sclerosis (ALS) remains still unclear. In the present study, we performed in vivo capillary imaging, directly measured spinal blood flow (SBF) and glucose metabolism, and analyzed whether if a possible flow–metabolism couplin...

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Autori principali: Miyazaki, Kazunori, Masamoto, Kazuto, Morimoto, Nobutoshi, Kurata, Tomoko, Mimoto, Takahumi, Obata, Takayuki, Kanno, Iwao, Abe, Koji
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2012
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293114/
https://ncbi.nlm.nih.gov/pubmed/22068226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2011.155
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