Early and progressive impairment of spinal blood flow–glucose metabolism coupling in motor neuron degeneration of ALS model mice

The exact mechanism of selective motor neuron death in amyotrophic lateral sclerosis (ALS) remains still unclear. In the present study, we performed in vivo capillary imaging, directly measured spinal blood flow (SBF) and glucose metabolism, and analyzed whether if a possible flow–metabolism couplin...

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Main Authors: Miyazaki, Kazunori, Masamoto, Kazuto, Morimoto, Nobutoshi, Kurata, Tomoko, Mimoto, Takahumi, Obata, Takayuki, Kanno, Iwao, Abe, Koji
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2012
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293114/
https://ncbi.nlm.nih.gov/pubmed/22068226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2011.155
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