Production of IL1-beta by ovarian cancer cells induces mesothelial cell beta1-integrin expression facilitating peritoneal dissemination

BACKGROUND: A crucial step in the metastatic spread of ovarian cancer (OC) is the adhesion and implantation of tumor cells to the peritoneal mesothelium. In order to study this step in the cascade, we derived a pro-metastatic human ovarian carcinoma cell line (MFOC3) from the non-metastatic FOC3 lin...

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Autores principales: Watanabe, Takafumi, Hashimoto, Toshihiro, Sugino, Takashi, Soeda, Shu, Nishiyama, Hiroshi, Morimura, Yutaka, Yamada, Hidekazu, Goodison, Steve, Fujimori, Keiya
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293087/
https://ncbi.nlm.nih.gov/pubmed/22296757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1757-2215-5-7
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