Production of IL1-beta by ovarian cancer cells induces mesothelial cell beta1-integrin expression facilitating peritoneal dissemination

BACKGROUND: A crucial step in the metastatic spread of ovarian cancer (OC) is the adhesion and implantation of tumor cells to the peritoneal mesothelium. In order to study this step in the cascade, we derived a pro-metastatic human ovarian carcinoma cell line (MFOC3) from the non-metastatic FOC3 lin...

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Detalhes bibliográficos
Main Authors: Watanabe, Takafumi, Hashimoto, Toshihiro, Sugino, Takashi, Soeda, Shu, Nishiyama, Hiroshi, Morimura, Yutaka, Yamada, Hidekazu, Goodison, Steve, Fujimori, Keiya
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293087/
https://ncbi.nlm.nih.gov/pubmed/22296757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1757-2215-5-7
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