Adolescent idiopathic scoliosis (AIS), environment, exposome and epigenetics: a molecular perspective of postnatal normal spinal growth and the etiopathogenesis of AIS with consideration of a network approach and possible implications for medical therapy

Genetic factors are believed to play an important role in the etiology of adolescent idiopathic scoliosis (AIS). Discordant findings for monozygotic (MZ) twins with AIS show that environmental factors including different intrauterine environments are important in etiology, but what these environment...

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Bibliographic Details
Main Authors: Burwell, R Geoffrey, Dangerfield, Peter H, Moulton, Alan, Grivas, Theodoros B
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293085/
https://ncbi.nlm.nih.gov/pubmed/22136338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-7161-6-26
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