Adolescent idiopathic scoliosis (AIS), environment, exposome and epigenetics: a molecular perspective of postnatal normal spinal growth and the etiopathogenesis of AIS with consideration of a network approach and possible implications for medical therapy

Genetic factors are believed to play an important role in the etiology of adolescent idiopathic scoliosis (AIS). Discordant findings for monozygotic (MZ) twins with AIS show that environmental factors including different intrauterine environments are important in etiology, but what these environment...

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Autores principales: Burwell, R Geoffrey, Dangerfield, Peter H, Moulton, Alan, Grivas, Theodoros B
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2011
Materias:
Review
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293085/
https://ncbi.nlm.nih.gov/pubmed/22136338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-7161-6-26
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