Why do results conflict regarding the prognostic value of the methylation status in colon cancers? the role of the preservation method

BACKGROUND: In colorectal carcinoma, extensive gene promoter hypermethylation is called the CpG island methylator phenotype (CIMP). Explaining why studies on CIMP and survival yield conflicting results is essential. Most experiments to measure DNA methylation rely on the sodium bisulfite conversion...

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Hlavní autoři: Tournier, Benjamin, Chapusot, Caroline, Courcet, Emilie, Martin, Laurent, Lepage, Côme, Faivre, Jean, Piard, Françoise
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293017/
https://ncbi.nlm.nih.gov/pubmed/22243995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-12
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