Why do results conflict regarding the prognostic value of the methylation status in colon cancers? the role of the preservation method

BACKGROUND: In colorectal carcinoma, extensive gene promoter hypermethylation is called the CpG island methylator phenotype (CIMP). Explaining why studies on CIMP and survival yield conflicting results is essential. Most experiments to measure DNA methylation rely on the sodium bisulfite conversion...

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Detaylı Bibliyografya
Asıl Yazarlar: Tournier, Benjamin, Chapusot, Caroline, Courcet, Emilie, Martin, Laurent, Lepage, Côme, Faivre, Jean, Piard, Françoise
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2012
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293017/
https://ncbi.nlm.nih.gov/pubmed/22243995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-12
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