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Concurrent hypermethylation of DNMT1, MGMT and EGFR genes in progression of gliomas
BACKGROUND: Gliomas are the most common neoplasm of the brain. High-grade gliomas often resist treatment even with aggressive surgical resection and adjuvant radiation and chemotherapy. Despite the combined treatment, they frequently recur with the same or higher-grade histology. Genetic instability...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3292961/ https://ncbi.nlm.nih.gov/pubmed/22264301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1746-1596-7-8 |
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