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Gene disruption of caspace-3 prevents MPTP-induced Parkinson's disease in mice

The development of Parkinson's disease is accompanied by concurrent activation of caspase-3 and apoptosis of dopaminergic neurons of human patients and rodent models. The role of caspase-3, a final executioner of apoptosis, in the pathogenesis of Parkinson's disease, however, remains to be...

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Bibliografische gegevens
Hoofdauteurs: Yamada, Marina, Kida, Kotaro, Amutuhaire, Willington, Ichinose, Fumito, Kaneki, Masao
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3292898/
https://ncbi.nlm.nih.gov/pubmed/20937256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.10.023
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