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Gene disruption of caspace-3 prevents MPTP-induced Parkinson's disease in mice
The development of Parkinson's disease is accompanied by concurrent activation of caspase-3 and apoptosis of dopaminergic neurons of human patients and rodent models. The role of caspase-3, a final executioner of apoptosis, in the pathogenesis of Parkinson's disease, however, remains to be...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3292898/ https://ncbi.nlm.nih.gov/pubmed/20937256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.10.023 |
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