Polo Like Kinase 2 Tumour Suppressor and cancer biomarker: new perspectives on drug sensitivity/resistance in cancer

The polo-like kinase PLK2 has recently been identified as a potential theranostic marker in the management of chemotherapy sensitive cancers. The methylation status of the PLK2 CpG island varies with sensitivity to paclitaxel and platinum in ovarian cancer cell lines. Importantly, extrapolation of t...

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Bibliografiske detaljer
Main Authors: Coley, Helen M., Hatzimichael, Eleftheria, Blagden, Sarah, McNeish, Iain, Thompson, Alastair, Crook, Tim, Syed, Nelofer
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2012
Fag:
Research Perspectives
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3292894/
https://ncbi.nlm.nih.gov/pubmed/22289679
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