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Polo Like Kinase 2 Tumour Suppressor and cancer biomarker: new perspectives on drug sensitivity/resistance in cancer

The polo-like kinase PLK2 has recently been identified as a potential theranostic marker in the management of chemotherapy sensitive cancers. The methylation status of the PLK2 CpG island varies with sensitivity to paclitaxel and platinum in ovarian cancer cell lines. Importantly, extrapolation of t...

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Detalhes bibliográficos
Main Authors: Coley, Helen M., Hatzimichael, Eleftheria, Blagden, Sarah, McNeish, Iain, Thompson, Alastair, Crook, Tim, Syed, Nelofer
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3292894/
https://ncbi.nlm.nih.gov/pubmed/22289679
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