cRGD-functionalized, DOX-conjugated, and (64)Cu-labeled superparamagnetic iron oxide nanoparticles for targeted anticancer drug delivery and PET/MR imaging

Multifunctional and water-soluble superparamagnetic iron oxide (SPIO) nanocarriers were developed for targeted drug delivery and positron emission tomography/magnetic resonance imaging (PET/MRI) dual-modality imaging of tumors with integrin α(v)β(3) expression. An anticancer drug was conjugated onto...

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Bibliographische Detailangaben
Hauptverfasser: Yang, Xiaoqiang, Hong, Hao, Grailer, Jamison J., Rowland, Ian J., Javadi, Alireza, Hurley, Samuel A., Xiao, Yuling, Yang, Yunan, Zhang, Yin, Nickles, Robert J., Cai, Weibo, Steeber, Douglas A., Gong, Shaoqin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3292876/
https://ncbi.nlm.nih.gov/pubmed/21367450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2011.02.006
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