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Cholesterol catabolism by Mycobacterium tuberculosis requires transcriptional and metabolic adaptations

To understand the adaptation of Mycobacterium tuberculosis to the intracellular environment, we used comprehensive metabolite profiling to identify the biochemical pathways utilized during growth on cholesterol, a critical carbon source during chronic infection. Metabolic alterations observed during...

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Detalhes bibliográficos
Main Authors: Griffin, Jennifer E., Pandey, Amit K., Gilmore, Sarah A., Mizrahi, Valerie, Mckinney, John D., Bertozzi, Carolyn R., Sassetti, Christopher M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3292763/
https://ncbi.nlm.nih.gov/pubmed/22365605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2011.12.016
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