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Clustering Induces a Lateral Redistribution of α2β1 Integrin from Membrane Rafts to Caveolae and Subsequent Protein Kinase C-dependent Internalization

Integrin α2β1 mediates the binding of several epithelial and mesenchymal cell types to collagen. The composition of the surrounding plasma membrane, especially caveolin-1- and cholesterol-containing membrane structures called caveolae, may be important to integrin signaling. On cell surface α2β1 int...

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Detalhes bibliográficos
Main Authors: Upla, Paula, Marjomäki, Varpu, Kankaanpää, Pasi, Ivaska, Johanna, Hyypiä, Timo, van der Goot, F. Gisou, Heino, Jyrki
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC329276/
https://ncbi.nlm.nih.gov/pubmed/14657242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-08-0588
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