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Biased signaling pathways in β(2)-adrenergic receptor characterized by (19)F-NMR
Extracellular ligand binding to G protein-coupled receptors (GPCRs) modulates G-protein and β-arrestin signaling by changing the conformational states of the cytoplasmic region of the receptor. Using site-specific (19)F-NMR labels in the β(2)-adrenergic receptor (β(2)AR) in complexes with various li...
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| Hoofdauteurs: | , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2012
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3292700/ https://ncbi.nlm.nih.gov/pubmed/22267580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1215802 |
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