Current paradigm of the 18-kDa translocator protein (TSPO) as a molecular target for PET imaging in neuroinflammation and neurodegenerative diseases

Neuroinflammation is a process characterised by drastic changes in microglial morphology and by marked upregulation of the 18-kDa translocator protein (TSPO) on the mitochondria. The continual increase in incidence of neuroinflammation and neurodegenerative diseases poses a major health issue in man...

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Autori principali: Ching, Alex Sik Chung, Kuhnast, Bertrand, Damont, Annelaure, Roeda, Dirk, Tavitian, Bertrand, Dollé, Frédéric
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer-Verlag 2011
Soggetti:
Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3292648/
https://ncbi.nlm.nih.gov/pubmed/22696004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13244-011-0128-x
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