Loading...
Osteogenesis Imperfecta Missense Mutations in Collagen: Structural consequences of a glycine to alanine replacement at a highly charged site
Glycine is required as every third residue in the collagen triple-helix, and a missense mutation leading to the replacement of even one Gly in the repeating (Gly-Xaa-Yaa)(n) sequence by a larger residue leads to a pathological condition. Gly to Ala missense mutations are highly underrepresented in o...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3292618/ https://ncbi.nlm.nih.gov/pubmed/22054507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201476a |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|