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Aberrantly methylated PKP1 in the progression of Barrett’s esophagus to esophageal adenocarcinoma

The aberrant DNA methylation of tumor suppressor genes occurs frequently in Barrett’s esophagus (BE) and esophageal adenocarcinoma (EAC) and likely affects the initiation and progression of BE to EAC. In the present study we discovered PKP1 as a novel methylated gene in EAC and then investigated the...

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Detalhes bibliográficos
Main Authors: Kaz, AM, Luo, Y, Dzieciatkowski, S, Chak, A, Willis, JE, Upton, MP, Leidner, RS, Grady, WM
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3292431/
https://ncbi.nlm.nih.gov/pubmed/22170739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.21923
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