Traversal of Multilayered Corneal Epithelia by Cytotoxic Pseudomonas aeruginosa Requires the Phospholipase Domain of ExoU

PURPOSE. Pseudomonas aeruginosa isolates from microbial keratitis are invasive or cytotoxic toward mammalian cells, depending on their type III secreted toxins. Cytotoxic strains express ExoU, a phospholipase that contributes to corneal virulence. This study determined whether the ExoU phospholipase...

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Bibliografiske detaljer
Main Authors: Ramirez, Julio C., Fleiszig, Suzanne M. J., Sullivan, Aaron B., Tam, Connie, Borazjani, Roya, Evans, David J.
Format: Artigo
Sprog:Inglês
Udgivet: Association for Research in Vision and Ophthalmology, Inc. 2012
Fag:
Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3292376/
https://ncbi.nlm.nih.gov/pubmed/22167094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-8999
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