Ablation of PI3K p110-α Prevents High-Fat Diet–Induced Liver Steatosis

OBJECTIVE: To determine whether the phosphoinositide 3-kinase (PI3K) catalytic subunits p110-α and p110-β play a role in liver steatosis induced by a high-fat diet (HFD). RESEARCH DESIGN AND METHODS: Liver-specific p110-α and p110-β knockout mice and control animals for each group were fed an HFD or...

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Hlavní autoři: Chattopadhyay, Mohar, Selinger, Elzbieta S., Ballou, Lisa M., Lin, Richard Z.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2011
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3292322/
https://ncbi.nlm.nih.gov/pubmed/21464441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0869
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