Induction of the Cyp1a-1 dioxin-responsive enhancer in transgenic mice.

Cyp1a-1, whose product, aryl hydrocarbon hydroxylase, assists in detoxification of polycyclic aromatic hydrocarbons, is the best characterized of the murine cytochrome P450 genes. The Cyp1a-1 dioxin-responsive enhancer region has been previously analyzed in vitro and found to induce expression of he...

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Bibliographic Details
Main Authors: Jones, S N, Jones, P G, Ibarguen, H, Caskey, C T, Craigen, W J
Format: Artigo
Language:Inglês
Published: 1991
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC329216/
https://ncbi.nlm.nih.gov/pubmed/1754392
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