Ca(2+)-mediated inhibition of a nuclear protein that recognizes UV-damaged DNA and is constitutively overexpressed in resistant human cells: DNA-binding assay.

A nuclear protein that recognizes UV-damaged DNA was detected from HeLa cells using DNA-binding assay. Treatment of cells with Ca2+ ionophore (A23187) caused a dramatic inhibition of the damage-recognition activity. In contrast, in vitro treatment of nuclear extracts with agents that affect protein...

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Hlavní autoři: Chao, C C, Huang, S L, Lin-Chao, S
Médium: Artigo
Jazyk:Inglês
Vydáno: 1991
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC329186/
https://ncbi.nlm.nih.gov/pubmed/1754377
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