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Targeting the p53 signaling pathway in cancer therapy - The promises, challenges, and perils
INTRODUCTION: Research over the past three decades has identified p53 as a multifunctional transcription factor, which regulates the expression of >2,500 target genes. p53 impacts myriad, highly diverse cellular processes, including the maintenance of genomic stability and fidelity, metabolism, l...
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| Formato: | Artigo |
| Idioma: | Inglês |
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2012
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3291789/ https://ncbi.nlm.nih.gov/pubmed/22239435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.2011.643299 |
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